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For instance, in a study involving human breast cancer cells treated with GPS, researchers observed an elevated Bax/Bcl-2 ratio, caspase activation, and a marked increase in apoptotic cells (Li et al., 2019)

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meanwhile, TNF- and IL-1 mRNA expressions were also significantly suppressed in DSS-induced colitis mice by gliotoxin treatment for 8 days, thus leading to the alleviation of the symptom of colonic inflammation in mice [49]

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